The offspring of older mothers don’t fare as well as those of younger mothers, in humans and many other species. They aren’t as healthy, or they don’t live as long, or they have fewer offspring themselves. A longstanding puzzle is why evolution would maintain this maternal effect in so many species since these late-born offspring are less fit to survive and reproduce.
In a new study in rotifers (microscopic invertebrates), scientists tested the evolutionary fitness of older-mother offspring in several real and simulated environments. They confirmed that this effect of older maternal age, called maternal effect senescence, does reduce evolutionary fitness of the offspring in all environments, primarily through reduced fertility during their peak reproductive period. They also suggest an evolutionary mechanism for why this may occur.
The study, led by Kristin Gribble of the Marine Biological Laboratory and Christina Hernández of Woods Hole Oceanographic Institution, was published in Proceedings of the National Academy of Sciences.
“Natural selection should weed out these less-fit offspring of older mothers. So why do we see this phenomenon across so many species?“ Hernández and collaborators found this pressure, called the selection gradient, declines with maternal age.
“Because the selection pressure decreases as the mothers age, it may not be strong enough to remove these less-fit offspring from the population,” Hernandez says. “Because of this, maternal effect senescence will persist and continue to evolve in the population, even though it results in decreased fitness,” Gribble adds. They don’t yet fully understand the genetic mechanisms that cause offspring quality to decrease with maternal age. From: Science Daily